(To learn more, see the Precautions for Prolia section below.). Also tell them if you smoke, drink alcohol, or use illegal drugs. Bone pain from Prolia may be most noticeable in your arms and legs. (With off-label use, a drug is used to treat conditions other than those its been approved to treat.) Do not shake the prefilled syringe. After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. You may wonder how Prolia compares with the alternative drug Reclast. Keep in mind that side effects of a drug can depend on: Additionally, you may experience different side effects from those listed below based on the condition youre treating with Prolia. Prolia may not be right for you if you have certain medical conditions or other factors that affect your health. The phase IV clinical study analyzes what interactions people who take Prolia and Calcium have. If you have any questions about Prolias side effects, talk with your doctor. After you stop taking Prolia, youre more likely to experience bone loss, and your risk of a vertebral fracture increases. If you want to stop taking Prolia, tell your doctor. More than half of American adults take an herbal or dietary supplement, and many more use over-the-counter or prescription drugs to manage maladies ranging from the occasional headache to chronic health conditions or mood disorders.. For many, it is part of their daily routine. Over time, Prolia can reduce bone loss and make your bones stronger. Your doctor will explain how Prolia will be given to you. You can use the study as a second opinion to make health care decisions. They may recommend ways to ease your symptoms and determine whether you should keep taking Prolia. It is not safe to receive Prolia during pregnancy. 2023 eHealthMe.com. So be sure to tell your doctor about all your health conditions before taking Prolia. Your doctor can help you decide which drug is better for your needs. Our phase IV clinical studies alone cannot establish cause-effect relationship. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Allergic reaction. Another common osteoporosis medication is denosumab (Prolia, Xgeva). to treat osteoporosis in males* and in females* whove gone through, to treat osteoporosis caused by long-term use of, metabolic bone disease, such as Hajdu-Cheney syndrome and juvenile. The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Be sure to read this information carefully each time. Prolias manufacturer also provides some self-injection instructions, as well as a video to show you how to inject Prolia. This medicine is only given in a clinic, doctor's office, or other health care setting and will not be stored at home. If youre concerned about weight gain with Prolia, talk with your doctor. But if you think youre having a medical emergency, call 911 or your local emergency number. It strengthens your bones by stopping certain bone cells called osteoclasts from breaking down your bones. Healthline Media does not provide medical advice, diagnosis, or treatment. If youd like to learn more about Prolia, talk with your doctor or pharmacist. * Approximation only. Youll receive Prolia doses from a healthcare professional. Now i am worried that i've been taking K2 which also takes calcium from the blood to the bones. The most common side effects of Prolia in women being treated for osteoporosis after menopause are back pain, pain in your arms and legs, high cholesterol, muscle pain, and bladder infection. There arent any studies that have compared these two drugs to each other. * For more information about this side effect, see Side effect specifics below. 2023 Healthline Media UK Ltd, Brighton, UK. For Xgeva, talk to your pediatrician regarding the use of this medicine in children. In rare cases, dental and jaw-related side effects have been reported with Prolia treatment. Last updated on Feb 8, 2023. Continue reading, Yes, Prolia does appear to weaken your immune system. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Pain, specifically musculoskeletal pain, is one of the most common side effects of Prolia. Mild side effects of Prolia that have been reported include: Mild side effects of many drugs may go away within a few days or a few weeks. This lowers your risk for bone fractures. Before starting Prolia treatment, talk with your doctor about any tooth procedures you have scheduled. Call your doctor right away if you have an allergic reaction to Prolia. With bone loss, your body loses old bone tissue faster than it makes new bone tissue. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Additionally, in Prolia-treated men with nonmetastatic prostate cancer receiving ADT, a greater incidence of cataracts was observed. You should also talk with them if you have any serious side effects during Prolia treatment. (Biologic medications are made from living organisms.). You should always consult your doctor or another healthcare professional before taking any medication. If you are a healthcare professional, click "I Agree" to continue. You should use an effective method of birth control (contraception) during treatment with Prolia and for at least 5 months after your last dose of Prolia. This drug may decrease your body's ability to fight infection. Call your doctor at once if you have: new or unusual pain in your thigh, hip, or groin; severe pain in your joints, muscles, or bones; skin problems such as dryness, peeling, redness, itching, blisters, bumps, oozing, or crusting; or. What osteoporosis medications are there, and what side effects do they have? Prolia (denosumab) and Reclast (zoledronic acid) are injections that can be used to treat or prevent osteoporosis in postmenopausal women. Before you have any dental work done, tell your dentist you are receiving this medicine. Talk with your doctor about which other treatments are better choices for you. If your Prolia treatment is stopped, talk to your doctor about other medicine that Prolia is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture Youll likely receive Prolia long term if you and your doctor decide that the drug is effective and safe for you. Because these reports happened after the studies, it isnt known for sure whether Prolia caused hair loss, or if it was due to another reason. While this drug may be prescribed for children as young as 13 years for selected conditions, precautions do apply. In fact, bone breakdown is higher in the first several months after you stop Prolia. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You may want to know how Prolia compares to the medication Tymlos. Calcium and Vitamin D: Important If you have questions about treatment options for osteopenia or arthritis, talk with your doctor. pain in bones and muscles, including back, arm, and leg pain, pain or swelling in the thigh or groin area. Side effects are possible with Prolia use, but in most cases they go away after a while. The risk is real, but rare. you may occur. If you have bothersome or severe side effects or other problems while taking Prolia and need to stop the medication, your doctor will monitor your bone mineral density. Follow your doctor's instructions about any restrictions on food, beverages, or activity. Talk to your health care professional or pharmacist for more information. Theyll do this with certain tests, such as a bone scan or ultrasound. Your doctor can discuss with you how to manage side effects and whether youll need to stop taking Prolia due to side effects. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. But if you think youre having a medical emergency, call 911 or your local emergency number. Brush and floss your teeth regularly while receiving this medication. Pregnancy. There is a potential for serious side effects to an unborn child. Prolia can also cause bones to not form correctly and reduced growth in a fetus. You can learn more about how we ensure our content is accurate and current by reading our. Find out which foods can help. Prolia is sometimes used in people whose bone fracture is caused by certain medicines or cancer treatments. It is important not to miss your dose. Monoclonal antibodies are made to target and destroy only certain cells in the body. Serious side effects from Prolia can occur, but they arent common. If you have a male* sexual partner, they should use birth control during this time as well. If you have low calcium levels, you should not take Prolia. After you have taken Prolia out of the refrigerator, you may keep it at room temperature for up to 14 days. It is created by eHealthMe based on reports of 8,432 people who take Prolia and Calcium from the FDA, and is updated regularly. Yes, if recommended by your doctor, you can stop taking Prolia. Take good care of your teeth and gums while you receive Prolia. You should make sure you get enough calcium and vitamin D while you are taking this medicine, unless your doctor tells you not to. Learn more about the FRAX score and the treatment options for, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. You might wonder how Prolia and the drug Xgeva compare. Since different people Prolia was the right choice for me because it worked for me and it was 1 shot every 6 months. * Sex and gender exist on spectrums. Learn more details about some of the side effects that Prolia may cause. Our website services, content, and products are for informational purposes only. Biosimilars usually cost less than brand-name drugs. Although its rare, your doctor may give you the option to self-inject Prolia at home. If youd like a detailed comparison of Prolia versus Boniva, view this article. Prolia Prolia 60 mg/1 mL in a single-dose prefilled syringe (medicine). Prolia Subcutaneous: Uses, Side Effects, Interactions, Pictures These medications have different active ingredients and they belong to different groups of drugs. Your risk for infection with Prolia may be higher if you have a weakened immune system. See additional information. MEDICATION GUIDE Prolia (PR-lee-a) (denosumab) They can treat the infection as needed. in your skin, lower stomach area (abdomen), bladder, or ear may happen. Continue reading, Prolia (denosumab) has not been associated with weight gain in clinical studies. Its also recommended that you use birth control while taking Prolia and for 5 months or more after your last dose. Your risk for some health conditions increases when you are postmenopausal. Specifically, Prolia is a monoclonal antibody (a lab-made protein). Specifically, Prolia works by blocking a protein called RANK. Increased risk of broken bones, including broken bones in the spine, after stopping, skipping or delaying Prolia. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Costs of prescription drugs can vary depending on many factors. Prolia can cause certain side effects, some of which are more common than others. Are there lifestyle changes that can help my osteoporosis. Prolia may lower the level of calcium in your blood. Dosage of drugs is not considered in the study. Prolia Side Effects: Common, Mild, and Serious - Healthline These factors include what your insurance plan covers. Prolia
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